Postdoctoral Position: Structural biology of the actin cytoskeleton
Max F. Perutz Laboratories
About the position
We employ an integrated approach by combining biochemistry, cell, chemical and structural biology approaches, including X-ray crystallography, small angle scattering and (starting) cryo-EM. The successful candidates will be involved in all aspects of the project, including protein expression, purification, biophysical, biochemical characterization and integrative structural biology.
About the project
The project is jointly funded by Austrian and Slovene Science Funds and is a close collaboration between the Djinovic group at Vienna, Austria, and the Pavsic group at the University of Ljubljana, Slovenia. The two young and dynamic groups will join forces to understand the detailed molecular mechanism of regulation of this essential F-actin crosslinking protein by calcium and specific phosphoprylation events.
The applicant should hold a PhD degree in a relevant field and two years of post-doctoral experience in a structural biology lab. Strong background in molecular cloning, expression, and purification of protein complexes is essential. Prior knowledge of crystallography and/or single-particle electron microscopy is needed. Excellent spoken and written English skills are required. The successful applicant will work in a stimulating scientific environment: Department for Structural and Computational Biology at the Max Perutz Labs, a joint venture between the University of Vienna and the Medical University of Vienna. The Labs are located at the Vienna BioCenter, the largest molecular life science hub in Austria.
We are equipped with state-of-the-art research infrastructure for experimental and computational work, and have access to facilities at the Vienna BioCenter Core Facilities, which include mass-spectrometry, a blend of Protein technologies and electron microscopy instruments (Glacios, Krios). Additionally the group has access to cryo-EM Titan-Krios through BAG at ESRF and to major European synchrotron high-brilliance X-ray sources.
A concise description of research experience, including a list of publishedpeer-reviewed articles.
Copy of the PhD diploma (or equivalent).
Contact details for three references, of which one should be your PhDsupervisor.
Please prepare the application as a single package in PDF format, and send it to [email protected], subject Postdoctoral position in Djinovic Lab.
Duration of employment: 3 years
Deadline of application: review of applications begins immediately and will continue until the position is filled.
For details in the project contact please contact: Kristina Djinovic Carugo [email protected]